Scientists make breakthrough in understanding stress

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Friday, April 22, 2011
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This is Leicestershire

A team of neuroscientists has made a breakthrough in understanding how the brain responds to traumatic events.

The discovery could lead to new treatments for stress-related psychiatric disorders.

Dr Robert Pawlak, from the University of Leicester, said: "It was known certain individuals are more susceptible to detrimental effects of stress.

"However, the reasons were not clear."

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Researchers, led by Dr Pawlak, found that the emotional centre of the brain – the amygdala – reacts to stress by increasing production of the protein neuropsin.

This triggers a series of chemical reactions including activating a gene that determines the stress response.

Blocking those proteins reduced stress levels.

Dr Pawlak said: "We are tremendously excited about these findings. Our discovery opens new possibilities for the prevention and treatment of stress-related psychiatric disorders such as depression and post-traumatic stress disorder."

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  • Profile image for This is Leicestershire

    by Graham, Whetstone

    Friday, April 22 2011, 3:56PM

    “- I know what you mean, Kulgan...

    when I've completed our regular supermarket shopping trip, one of the thoughts that often crosses my mind is that these people who cannot manoeuvre a trolley with any consideration for others will be driving a vehicle on the roads with the same aplomb... scary.”

  • Profile image for This is Leicestershire

    by Rich, Leicester

    Friday, April 22 2011, 3:01PM

    “Delighted to see some research going into causes and remedies for mental illness. All credit to Dr Pawlak and his team... keep up the good work”

  • Profile image for This is Leicestershire

    by Kulgan, Crydee

    Friday, April 22 2011, 12:32PM

    “I understand Stress.

    This morning I took my Mother shopping in Asda Hinckley (other supermarkets are available) for her weekly shop . It was horrendous. There must have been 5 million people doing their shopping (may be exagerating slightly ;) ) but it was full to the rafters.

    The shop is only closed on Easter Sunday!!!

    When I got home to Castle Crydee, the stress went away ;)”

  • Profile image for This is Leicestershire

    by Hoping to be happy, Knighton

    Friday, April 22 2011, 10:24AM

    “Thank You! A reason for funding universites research, whilst we do not agree with student Fees this work would be differcult if they were having to chase funding to do their research!”

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